
At Bone Biologics, we’re transforming bone regeneration with NELL-1, our proprietary recombinant human protein growth factor. The first-in-human study is now underway with this powerful and potent growth factor that has been shown in animal models to enhance both the quantity and quality of bone.
Efficacy
Accelerates spine fusion or fracture healing
Safety
Forms bone only in targeted areas without inducing inflammation or unwanted bone formation.
We are conducting a pilot clinical study with NB1 as a bone graft substitute for spine fusion patients with the goal of providing rapid, specific and guided bone regeneration. NB1 is comprised of rhNELL-1 plus demineralized bone matrix.



We are harnessing the transformative power of NELL-1 to redefine the future of bone regeneration. Our commitment is to revolutionizing spinal fusion and other bone-related procedures with our advanced solutions that improve clinical outcomes while reducing healthcare costs. We are exploring new frontiers for NELL-1 to unlock its full potential for enhanced bone healing and regeneration.

Jeff Frelick
Chief Executive Officer
Don Hankey
Chairman